AORTIC THROMBOSIS AFTER CARDIAC SURGERY FROM HEPARIN-INDUCED THROMBOCYTOPENIA
نویسندگان
چکیده
منابع مشابه
Heparin-induced thrombocytopenia and cardiac surgery.
Unfractionated heparin given during cardiopulmonary bypass is remarkably immunogenic, as 25% to 50% of postcardiac surgery patients develop heparin-dependent antibodies during the next 5 to 10 days. Sometimes, these antibodies strongly activate platelets and coagulation, thereby causing the prothrombotic disorder, heparin-induced thrombocytopenia. The risk of heparin-induced thrombocytopenia is...
متن کاملHeparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملHeparin induced thrombocytopenia causing an isolated cardiac free floating thrombosis.
1010-7940/$ see front matter Q 2005 Elsevier B.V. All rights reserved. doi:10.1016/j.ejcts.2005.04.011 * Corresponding author. Address: Service de Chirurgie Thoracique et Cardiovasculaire, Centre Hospitalier Régional et Universitaire, avenue du Général Koenig, 51092 Reims Cedex, France. Tel.: C33 3 26 78 71 05; fax: C 33 3 26 78 32 73. E-mail address: [email protected] (S. Rubin). 1 Heparinoid Proto...
متن کاملThrombosis due to Heparin-induced Thrombocytopenia in Cardiac Surgery: is Fondaparinux an Effective Treatment?
Objective: To determine whether fondaparinux is effective in the treatment of thrombosis due to heparin-induced thrombocytopenia (HIT) in cardiac surgery we reported three cases successfully treated with fondaparinux and withdrawal of all heparins. Patients: All three patients were female and underwent heart valve replacement using cardiopulmonary bypass. Combined clinical criteria, "4T score" ...
متن کاملHeparin-induced thrombocytopenia in cardiac surgery and critically ill patients.
Thrombocytopenia as well as anti-platelet factor 4/heparin (PF4/H) antibodies are common in cardiac surgery patients and those treated in the intensive care unit. In contrast, heparin-induced thrombocytopenia (HIT) is uncommon in these populations (~1 % and ~0.5 %, respectively). A stepwise approach where testing for anti-PF4/H antibodies is performed only in patients with typical clinical symp...
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ژورنال
عنوان ژورنال: Chest
سال: 2020
ISSN: 0012-3692
DOI: 10.1016/j.chest.2020.08.691