Anxiolytic- and antidepressant-like effects of the methadone metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP)
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چکیده
منابع مشابه
Antidepressant- and anxiolytic-like effects of methanolic extract of Salvia spinosa L. in mice
Introduction: Development of new medicines with fewer adverse effects and more efficacies is needed for the treatment of psychiatric disorders. The present study aimed to investigate the putative antidepressant and anxiolytic effects of methanolic extract of Salvia spinosa L. (SS) in mice. Materials and Methods: Elevated plus-maze (EPM) and open field tests (OFT) were conducted to evaluate anti...
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The title compound, C(17)H(16)O(3)S, was prepared by the oxidation of 5-ethyl-2-methyl-3-phenyl-sulfanyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring makes a dihedral angle of 75.94 (8)° with the plane of the benzofuran fragment. The crystal structure is stabilized by π-π inter-actions between the furan rings of neighbouring mol-ecules [centroid-centroid distance = 3.620 (4) ...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2016
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2015.09.012