Antiviral Therapy in Children with Hydroa Vacciniforme

Antiviral therapy in children with hydroa vacciniforme.

Hydroa vacciniforme is a rare, usually quite severe, photo-dermatosis. Association with Epstein-Barr virus infection and a possibly increased risk of lymphoproliferative malignancy have been demonstrated. We describe here four patients with Epstein-Barr virus-associated hydroa vacciniforme treated with acyclovir/valacyclovir therapy with a good clinical response. The children were reported to h...

Hydroa vacciniforme.

CMAJ © 2010 Canadian Medical Association or its licensors 1 A10-year-old boy presented with a three-year history of recurrent lesions on photoexposed areas that worsened each summer. The boy had no family history of photosensitivity. Some vesicles and tiny depressed scars resembling chickenpox scars were present on his arms, face and ears. He had freckles on his face and a deep ulcer covered wi...

Extensive hydroa vacciniforme*

Hydroa Vaciniforme is a very rare photodermatosis that is mainly seen in childhood. An 18 year old female student reported that since the age of 5 she has been suffering necrotic lesions and vesicles lesions in exposed areas, leaving asymptomatic varioliform scars, which worsened in summer. Light microscopy showed epidermal necrosis with lymphocytic infiltration . Sunscreens were prescribed wit...

Hydroa vacciniforme affecting the eye.

A case of hydroa vacciniforme.

Hydroa vacciniforme (HV) is a rare and chronic pediatric disorder that is characterized by photosensitivity and recurrent vesicles that heal with vacciniforme scarring. The pathogenesis of HV is unknown; no chromosome abnormality has been identified. HV patients have no abnormal laboratory results, so the diagnosis of HV is based on identifying the associated histological findings in a biopsy s...