Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs
نویسندگان
چکیده
منابع مشابه
Inactivated parapoxvirus ovis (Orf virus) has antiviral activity against hepatitis B virus and herpes simplex virus.
It is known that some viruses are able to induce vigorous immune reactions. This study shows that inactivated parapoxvirus ovis (Orf virus), strain D1701 (PPVO), induces an autoregulatory cytokine response that involves the upregulation of IL-12, IL-18, IFN-gamma and other T helper 1-type cytokines and their subsequent downregulation, which is accompanied by induction of IL-4. An increase in IL...
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ژورنال
عنوان ژورنال: Antiviral Research
سال: 2007
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2006.09.008