Antitumor activity of tetrahydroisoquinoline analogues 3-epi-jorumycin and 3-epi-renieramycin G
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منابع مشابه
Synthesis and activity of 3-epi-actinobolin.
3-epi-Actinobolin was synthesized by the chemical transformation of actinobolin involving a key step of the reconstruction of fused delta-lacton skeleton via intramolecular acylation reaction. The analogue with low toxicity weakly inhibits Gram-positive and Gram-negative bacteria.
متن کامل3'-Deamino-4'-epi-3'-hydroxy-daunorubicin and -doxorubicin. Synthesis and antitumor activity.
3'-Deamino-4'-epi-3'-hydroxy-daunorubicin (11) and -doxorubicin (14) have been synthesized. In the in vivo murine P-388 lymphocytic leukemia assay, these two compounds were more active than daunorubicin (1) and doxorubicin (2), respectively. Comparative studies in the P-388 assay indicated 3'-deamino-3'-hydroxydoxorubicin (3) to be more active than its 4'-epimer 14.
متن کاملApplications of Epi-Retractable and Co-Epi-Retractable Modules
A module M is called epi-retractable if every submodule of M is a homomorphic image of M. Dually, a module M is called co-epi-retractable if it contains a copy of each of its factor modules. In special case, a ring R is called co-pli (resp. co-pri) if RR (resp. RR) is co-epi-retractable. It is proved that if R is a left principal right duo ring, then every left ideal of R is an epi-retractable ...
متن کاملOptimized 3 T EPI of the amygdalae.
The optimum parameters for single-shot gradient-recalled (GR) EPI-based fMRI studies of the limbic region are systematically established at 3 T via their ability to mitigate intravoxel dephasing-measured via SNR and T2* in the amygdalae-and their implications for temporal resolution (or brain coverage). Conventional imaging parameters (64 x 64 matrix size and 4-6 mm thick slices) are confirmed ...
متن کاملErratum: Applications of epi-retractable and co-epi-retractable modules
In this errata, we reconsider and modify two propositions and their corollaries which were written on epi-retractable and co-epi-retractable modules.
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry Letters
سال: 2006
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2006.03.042