Antioxidant Supplements and Gastrointestinal Diseases

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Antioxidant Supplements and Gastrointestinal Diseases: A Critical Appraisal.

The gastrointestinal tract digests and absorbs dietary nutrients, protects the body against physical and chemical damage from contents in its lumen, provides immunity against external antigens, and keeps an optimum environment for the gut microbiota. These functions cannot be performed normally in several diseases of which the following are discussed here: irritable bowel syndrome and inflammat...

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Antioxidant supplements and mortality.

To the Editor: Based on their meta-analysis of antioxidant supplementation trials, Dr Bjelakovic and colleagues 1 conclude that some of the intervention nutrients appeared to be associated with increased mortality. Particular aspects of their approach, analysis, and reported findings may have led to incomplete or biased determinations of the real effect of such nutrients in various populations....

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Reactive oxygen species and antioxidant defense in human gastrointestinal diseases

Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases (IBDs), and celiac disease are the most common disorders affecting not only adults but also children. Both IBDs and celiac disease are associated with oxidative stress, which may play a significant role in their etiologies. Reactive oxygen species (ROS) such as superoxide radicals (O2•-), hydroxyl radicals (•O...

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Surviving antioxidant supplements.

An association between healthy diet and good health has been noted since Hippocrates (460 – 377 bc) — and in fact long before (1). Our diet provides numerous vitamins and trace elements that are essential to good health. Observational studies have shown that there is a positive association between a healthy diet, especially high intake of fruits and vegetables, and delayed aging, reduced risk o...

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Antioxidant supplements to prevent mortality.

CLINICAL QUESTION Are antioxidant supplements associated with higher or lower all-cause mortality? BOTTOM LINE Antioxidant supplements are not associated with lower all-cause mortality. Beta carotene, vitamin E, and higher doses of vitamin A may be associated with higher all-cause mortality.

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ژورنال

عنوان ژورنال: Medical Principles and Practice

سال: 2017

ISSN: 1011-7571,1423-0151

DOI: 10.1159/000477304