Antioxidant Dose Response in Human Blood Cells Exposed to Different Types of Irradiation
نویسندگان
چکیده
منابع مشابه
Quantitation of genome damage and transcriptional profile of DNA damage response genes in human peripheral blood mononuclear cells exposed in vitro to low doses of neutron radiation
Background: Humans are exposed to ionizing radiation from different sources that include natural, occupational, medical, accidental exposures. Evaluation of the effect of low level of neutron exposure to human cells in vitro has important implications to human health. Attempts were made to measure genome damage, transcriptional profile of DNA damage response and repair genes in peripheral blood...
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Radiation exposure is a threat to public health because it causes many diseases, such as cancers and birth defects, due to genetic modification of cells. Compared with the past, a greater number of people are more frequently exposed to higher levels of radioactivity today, not least due to the increased use of diagnostic and therapeutic radiation-emitting devices. In this study, ultra-performan...
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hematopoietic lineages, and are extremely sensitive to oxidative stresses. Exposure of HSPCs to ionizing radiation causes a marked suppression of mature blood cell production in a dosedependent manner. However, little information about the long-term effects of low-dose X-irradiation on the stemness of human HSPCs has been reported. The present study investigated the biological characteristics o...
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Past work has shown that exposure to gamma rays and protons elicit a persistent oxidative stress in rodent and human neural stem cells (hNSCs). We have now adapted these studies to more realistic exposure scenarios in space, using lower doses and dose rates of these radiation modalities, to further elucidate the role of radiation-induced oxidative stress in these cells. Rodent neural stem and p...
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Introduction: Cancer is, in essence, a genetic disease and is the second leading cause of death globally. Fortunately, many common types of cancer are treatable if detected early and of course there are many medications and treatments available today. Among the new methods to treat cancer, radiotherapy seems to be hopeful in patients with malignancies. This work investigates th...
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ژورنال
عنوان ژورنال: Journal of Medical Sciences
سال: 2001
ISSN: 1682-4474
DOI: 10.3923/jms.2001.133.136