Antioxidant activity of <i>Vaccinium axillare</i> Nakai fruits during oxidative stress <i>in vivo</i>

Intensity of free radical oxidation processes in vivo (model induced oxidative stress) was studied after the probe introduction Vaccinium axillare Nakai fruit extract. Material and methods. Four groups (n = 40) white male CBA mice weighing 20–25 g were included experiment: 1 – intact control; 2–0.9 % sodium chloride solution administered per os for 10 days a dose ml/kg/day; 3 group “cisplatin” (animals received 0.9 similarly to 2, on fifth day experiment cisplatin once by intraperitoneal injection at 7.5 mg/kg); 4 “cisplatin + blueberries” (mice extract Blueberry axillary fruits ml/kg/day days, mg/kg). Antioxidant activity chemiluminescence. Results discussion. Analysis kinetic parameters mouse kidney homogenate chemiluminescence showed that stress develops animals single cisplatin, decreases its severity. Conclusions. Bilberry (Vaccinium Nakai) has pronounced antioxidant properties may be important treatment prevention diseases associated with stress.