Antinükleer Antikor Pozitif Hastalarda Test İsteme Nedenleri ve Hastaların Nihai Tanıları

Background: The aim of this study was to determine the reasons for request antinuclear antibody (ANA) in ANA-positive patients and final diagnosis these whether they developed a rheumatologic disease. Method: In retrospective study, files 559 with positive ANA were reviewed. Demographic, laboratory clinical characteristics noted. At end follow-up, recorded. Results: included 346 patients. 233 female, 113 male. mean age at time positivity 9.4  4.7 years, follow-up period 19 5.7 months. most common symptom myalgia/arthralgia (21.7%). Other urticaria, abdominal pain, thrombocytopenia, proteinuria. Extractable nuclear antigens (ENA) panel results negative 170 (49.1%). ENA panel, dense fine speckled antigen 70 antibodies frequently 135 (39.2%). 234 had no One hundred one diagnosed non-rheumatologic diseases, 11 diseases. Eleven diseases girls. Rash predictive value disease 3.2% 1.7% systemic lupus erythematosus. Conclusions: Due low testing, risk autoimmune should be identified carefully evaluated before is requested.