Antinuclear antibody-negative systemic sclerosis

Antinuclear antibody-negative systemic lupus erythematosus - how common?

A review of five years' DNA-binding antibody results in a routine service laboratory revealed 38 patients who had high DNA-binding capacity (DNA-bc) but no antinuclear antibodies (ANA). On retrospective case note analysis, 22 patients (58%) were thought to have systemic lupus erythematosus (SLE), although only six (16%) fulfilled the preliminary classification criteria of the American Rheumatis...

Antinuclear antibodies in systemic sclerosis

Antinuclear antibodies associated with pulmonary involvement in systemic sclerosis.

In response to Dr. Homasson, my comments are as follows: 1) Mv paper is about a personal experience with laser bronchoscopy Ofll\ 2) In the introductii)n, I mentioned a statenient by Dr. Shapshav drawn from reference 1 of my paper. 3) I have flO personal experience with that technique and therefore I am unable to judge Dr. Honiasson’s letter. I think Dr. Shapshay or Dr. Sanderson, who initiated...

Antireticulin antibody in systemic sclerosis.

The prevalence, immunoglobulin class, and IgG subclass of antireticulin antibody in the serum samples of 32 patients with systemic sclerosis were investigated by indirect immunofluorescence on unfixed rodent tissue. Antireticulin antibody was present in 22/32 (69%) of patients and belonged to the IgG class in 19/22 (86%), the IgA class in 13/22 (59%), and the IgM class in 6/22 (27%) of positive...

Ocular, systemic and antinuclear antibody changes with acebutolol.

A group of 29 hypertensive patients were studied for side effects of acebutolol. An antinuclear antibody titre of >/=1/64 developed in 23 per cent of patients during a 12-month course of treatment. Full ophthalmic examination before and after the treatment period showed a statistically significant increase in tear secretion at one year. One patient had a slight worsening of her psoriasis. No pa...