Antineoplastic Effect of Iodine-125-labelled Iododeoxyuridine
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Preparation and evaluation of 211At labelled antineoplastic antibodies.
PURPOSE The objective of this study was to determine and verify the stability of 211At-labelled antibodies under physiological conditions and their specific cell-binding capacity for selected epitopes, in order to evaluate the potential of 211At for alpha-radioimmunotherapy. METHODS 211At was produced at the department's cyclotron and was linked via the intermediate 3-211At-succinimidyl-benzo...
متن کاملRadiotoxicity of iodine-125-labeled oligodeoxyribonucleotides in mammalian cells.
UNLABELLED We investigated the distribution, stability and radiotoxicity of 125I-oligodeoxyribonucleotides (125I-ODN) in human fibrosarcoma HT-1080 cells to study the radiotoxic effects of the Auger electron emitter 125I delivered to the cells by ODN. METHODS We delivered 125I-ODN into the cells via complexing with a liposomal delivery system. To assess the intracellular distribution and stab...
متن کاملIodine-125-fibrinogen kinetics in the rabbit arterial wall.
Elevated fibrinogen has been claimed as an independent risk factor for the development of atherosclerosis. Incorporation of fibrinogen into human atherosclerotic lesions has been demonstrated. We assessed in a rabbit model of experimental atherosclerosis, biodistribution as well as kinetics and vascular uptake of (125)I-fibrinogen. Rabbits aged 6 months were fed a 1% cholesterol supplemented di...
متن کاملA simple, solid-phase iodine-125 radioimmunoassay for theophylline.
The activity of y-glutamyltransferase (EC 2.3.2.2) is measured on the DuPont aca by an adaptation of the Szasz procedure ;-y-glutamyl-p-nitroanilide is transferred to glycylglycine, thereby releasing p-nitroaniline, which is measured at 405 nm. I have noticed low glutamyltransfer-ase activity in patients with cholestasis wherealkaline phosphate (EC 3.1.3.1) is increased, total bilirubin> 100 mg...
متن کاملP 112 Choroidal melanoma brachytheraphy with iodine 125
suasbourg calme anticilncere " x Paul Strauss Fwpose : llte auhon repwt their short and mean term results in a series of 41 @en& veawd with I 125 brxhylherapy for weal or ciliary bcdy melanomas with minimal follow up of one year. Methods : Among the 47 patients treated wilh I 125 brachylherapy for inlraoadar melanomas ne selected 41 oatienu wkh minimal follow-up of one year. The dose delivered ...
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ژورنال
عنوان ژورنال: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
سال: 1975
ISSN: 0020-7616
DOI: 10.1080/09553007514550521