Antiidiotypic IgG crossreactive with Rh alloantibodies in red cell autoimmunity

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Antiidiotypic IgG crossreactive with Rh alloantibodies in red cell autoimmunity.

IgG autoantibodies eluted from RBCs of antiglobulin positive normal blood donors contained at least two antibody populations, an IgG autoantibody (Ab 1), and an IgG population (Ab 2) that agglutinated RBCs coated with some Rh(D) alloantibodies. Eight of 24 autoantibody eluates tested agglutinated 3 of 10 anti-Rh(D) sensitized RBCs. The agglutinating activity was inhibited specifically by preinc...

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Red cell alloantibodies in Lao blood donors.

Data of the prevalence of red cell alloantibodies in blood donors will assist in improving safe blood supply for patients needing transfusion. The purpose of this study was to determine prevalence of red cell alloantibodies in Lao blood donors. Antibody screening and identification by multiple phase indirect antiglobulin standard tube assay were performed in serum samples from 1,181 blood donor...

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Prevalence and specificities of red cell alloantibodies in transfusion-dependent beta thalassemia patients in Yazd

Abstract Background Multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. In this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. Materials and Methods In this cross-sectional study, overa...

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Frequency of irregular red cell alloantibodies in patients with thalassemia major: a bicenter study.

OBJECTIVE To provide frequency and distribution pattern of various types of irregular red cell alloantibodies in patients with thalassemia major. METHODS This is a descriptive study conducted at two centers from January to December 2001. Purposive sampling was done and all patients diagnosed to have thalassemia major were included in the study. Antibody identification was carried out on serum...

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ژورنال

عنوان ژورنال: Blood

سال: 1987

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v70.3.710.bloodjournal703710