Antigenicity of Ehrlich Ascites Tumor

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Antibody formation for malignant tumor. 3. Antigenicity of peptide of ribosomal digest in Ehrlich ascites tumor.

Antigenicity of the peptide of ribosomal digest in Ehrlich ascites tumor was studied. The peptide was purified by DEAE Sephadex A-50 column chromatography. The peptide was electrophoretically basic, single, and 1.32 S20w sedimentation coefficient with poor content of tyrosine and phenylalanine. The maximum absorbancy was at 267 mμ. Mice and rabbits were immunized with the mixture of the purifie...

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Antibody formation for malignant tumor. II. Antigenicity of Ehrlich ascites tumor lipoprotein.

A unique low density lipoprotein was obtained from the tumor transplanted with a cultured cell line of Ehrlich ascites tumor, JTC-ll cell. The tumor low density lipoprotein electrophoretically migrated as a single band, and the mobility was different from that of other organs. The chemical composition of lipid, cholesterol and phospholipids in tumor low density lipoprotein were characteristic. ...

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Metabolism of phospholipids in Ehrlich ascites tumor.

of cancer cells may be related to the characteristics of the cell surface membranes (i, 7, 43). For example, Coman and his associates have drawn attention to the importance of such properties of the cell surface as adhesiveness(6, 31) and stickiness (8). Since it is now known that lipids, and in particular phospholipids, are essential components of all cell membranes, including both the plasma ...

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Effect of hydrocortisone on Ehrlich ascites tumor.

The effect of hydrocortisone acetate (HCA) on three cell lines of Ehrlich ascites tumors was investigated in four strains of mice. It was attempted to separate the immunological aspects from the hormonal influence in the cortisone treatment of the tumors. HCA significantly inhibited the growth of ascitic hypotetraploid Ehrlich stock in Swiss mice, and to a lesser extent that of ascitic hypotetr...

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Cholesterol metabolism in the Ehrlich ascites tumor.

account for only about 3% of the cholesterol accumulation in the Ehrlich cells. Since the peritoneal fluid in which the tumor cells grow is rich in very-low-density lipoproteins (VLDL), we wished to determine whether the cholesterol contained in these VLDL might be available for utilization by the cells. During incubation in vitro at 37°,the Ehrlich cells took up large quantities of cholestero...

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ژورنال

عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)

سال: 1968

ISSN: 0030-1558,1882-4528

DOI: 10.4044/joma1947.80.7-8_691