Antigen variability in Anaplasma phagocytophilum during chronic infection of a reservoir host
نویسندگان
چکیده
منابع مشابه
Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection
Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat shock protein 70 (HSP70) were shown to be localized on the bacterial membrane, with a possible role during pathogen infection in ticks. In this study, we hypothesized that A. p...
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Fourteen vertebrate species (10 mammals and 4 birds) were assessed for their ability to transmit Anaplasma phagocytophilum, the bacterium that causes human granulocytic anaplasmosis, to uninfected feeding ixodid ticks. Small mammals were most likely to infect ticks but all species assessed were capable of transmitting the bacterium, in contrast to previous findings.
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Ticks may transmit pathogens to ruminants worldwide, creating diseases such as anaplasmosis, babesiosis, ehrlichiosis and theileriosis. In Europe, the most important tick vector is Ixodes ricinus and the most widespread tick-borne infection in animals is Anaplasma phagocytophilum. This infection causes tick-borne fever (TBF) in ruminants, a disease which may not only cause suboptimal growth, bu...
متن کاملTypical and atypical manifestations of Anaplasma phagocytophilum infection in dogs.
Eighteen clinically ill dogs, naturally infected with Anaplasma phagocytophilum, were examined at a veterinary practice in Baxter, Minnesota. A clinical examination, complete blood cell count, enzyme- linked immunosorbent assay (ELISA) for A phagocytophilum, Borrelia burgdorferi, and Ehrlichia canis antibodies and Dirofilaria immitis antigen, and a polymerase chain reaction test for A phagocyto...
متن کاملPrevalence of Anaplasma phagocytophilum infection in feral cats in Massachusetts
Objectives The primary objective of this study was to determine the prevalence of Anaplasma phagocytophilum infection and exposure in adult feral cats in Massachusetts, an endemic area for A phagocytophilum and its tick vector Ixodes scapularis. The secondary objective was to determine if there were correlations between A phagocytophilum infection and the presence of anemia and thrombocytopenia...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2012
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.059808-0