Antifungal Effect of Non-Woven Textiles Containing Polyhexamethylene Biguanide with Sophorolipid: A Potential Method for Tinea Pedis Prevention

Antifungal Effect of Non-Woven Textiles Containing Polyhexamethylene Biguanide with Sophorolipid: A Potential Method for Tinea Pedis Prevention

Tinea pedis is a preventable skin disease common in elderly or diabetic patients. Daily foot washing is effective for prevention, but can be difficult for many patients. Additionally, conventional methods cannot eliminate fungi within the stratum corneum, a common site for fungal invasion. This study investigates the antifungal effects, cytotoxicity, permeability, and efficacy of non-woven text...

Evaluating a dressing impregnated with polyhexamethylene biguanide

Aims: To evaluate a new polyhexamethylene biguanide (PHMB) foam dressing for inclusion in the specialist dressing section of a trust’s wound management formulary. Methods: KendallTM AMD (Covidien) antimicrobial foam dressing’s use was reviewed through a retrospective evaluation of patients who had been treated with the dressing. Data was collected from the medical and nursing notes of 25 patien...

Tinea Pedis

Polyhexamethylene biguanide and calcineurin inhibitors as novel antifungal treatments for Aspergillus keratitis.

PURPOSE To establish polyhexamethylene biguanide (PHMB) as an effective treatment for Aspergillus keratitis in a novel murine model. To determine the ability of the calcineurin inhibitors tacrolimus (FK506) and cyclosporine A (CSA) to enhance the activity of PHMB, amphotericin B (AMB), and voriconazole (VCZ) against Aspergillus keratitis. METHODS IN VITRO STUDIES Broth antifungal susceptib...

Evaluation of polyhexamethylene biguanide (PHMB) as a disinfectant for adenovirus.

IMPORTANCE Swimming pools can be a vector for transmission of adenovirus ocular infections. Polyhexamethylene biguanide (PHMB) is a disinfectant used in swimming pools and hot tubs. OBJECTIVE To determine whether PHMB is an effective disinfectant against ocular adenovirus serotypes at a concentration used to disinfect swimming pools and hot tubs. DESIGN In vitro laboratory study. INTERVEN...