Antifungal Antibiotics and Breakthrough Bacteremias

Polyene Antifungal Antibiotics

ZYGMUNT, WALTER A. (Mead Johnson Research Center, Evansville, Ind.). Intracellular loss of potassium in Candida albicans after exposure to polyene antifungal antibiotics. Appl. Microbiol. 14:953-956. 1966.-Eleven antifungal antibiotics, representing three broad macrolide classes, were studied in Candida albicans for their effect on growth and on the fate of intracellular K+. Marked differences ...

Evolution of Antibiotic Tolerance During Oxacillin, Daptomycin and Dalbavancin Therapy Results in Breakthrough Staphylococcus aureus Bacteremias

Penicillin: Breakthrough to the Era of Antibiotics

this specialty fruit and was responsive to the industry need for reliably tested freestone varieties. A sequence of similar varieties over a period as long as for peaches is envisioned. As was true with peaches, main crop apricot varieties were static for many years. As a consequence, the varieties, mostly of European origin, became less well suited to changing market demands. Commercial drying...

Paper chromatography of antifungal antibiotics.

Paper chromatography is very helpful in the identification and comparison of antibiotics, but very few results from the application of this technique have been published so far. The awakening of interest in the search for antibiotics which are active against fungi pathogenic to plants and animals makes the investigator aware of the scant information that is available to help characterize such a...

[New antifungal antibiotics, bacillopeptins and fusaricidins].

We isolated four strains of bacteria producing antifungal antibiotics from the rhizosphere of garlic with basal rot caused by the plant pathogenic fungal strain Fusarium oxysporum. Among them, Bacillus subtilis FR-2 was found to produce new antifungal antibiotics, named bacillopeptins A, B, and C. Their structures have been determined by 1D and 2D NMR and MS experiments, and amino acid analysis...