ANTIDERMATOPHYTIC ACTIVITY OF STREPTOMYCES CACAOI SUBSP. CACAOI. M20
نویسندگان
چکیده
منابع مشابه
Scalp abscess due to Streptomyces cacaoi subsp. cacaoi, first report in a human infection.
Streptomyces cacaoi subsp. cacaoi, a Gram-positive, branching filamentous bacteria, was isolated from a scalp infection in a patient from Pondicherry, India. Phenotypic tests identified the isolate as a Streptomyces species, but 16S rRNA sequence analysis provided the species identification required for tracking of this emerging pathogen.
متن کاملpolR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis.
The polyoxin (POL) biosynthetic gene cluster (pol) was recently cloned from Streptomyces cacaoi subsp. asoensis. A 3.3 kb DNA fragment carrying an obvious open reading frame (polR), whose deduced product shows sequence similarity to SanG of Streptomyces ansochromogenes and PimR of Streptomyces natalensis, was revealed within the pol gene cluster. Disruption of polR abolished POL production, whi...
متن کاملThe active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.
The active-site serine of the extracellular beta-lactamases of Streptomyces cacaoi and Streptomyces albus G has been labelled with beta-iodopenicillanate. The determination of the sequence of the labelled peptides obtained after trypsin digestion of the denatured proteins indicate both enzymes to be class A beta-lactamases. Surprisingly the two Streptomyces enzymes do not appear to be especiall...
متن کاملMechanisms of acquired penicillin-resistance in Streptomyces cacaoi. Role of penicillin-binding proteins in penicillin resistant mutants.
Several mutants isolated after N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis of Streptomyces cacaoi strain KCCS-0352, were resistant to benzylpenicillin ranging in concentration from 1,000 to 5,000 micrograms/ml (4- to 20-fold more resistant than the parent). These mutants also acquired resistance to mecillinam, cephamycin C and methicillin. The affinity for beta-lactams of penicillin-bindin...
متن کاملAntidermatophytic activity of essential oils
The increasing impact of dermatophytic infections, the limitations encountered in their treatments (e.g. resistance, sideeffects, and high toxicity), the rising overprescription and overuse of conventional antifungals and high treatment costs all have stimulated the research for alternative natural drugs, such as essential oils. This paper reviews the in vitro/in vivo activity of essential oils...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2017
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2017.v10i7.18270