Antidepressant-like effects of intracerebroventricular FGF2 in rats
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Evaluation of antidepressant-like effects of aqueous and ethanolic extracts of Pimpinella anisum fruit in mice
Objective: Pimpinella anisum (P. anisum) has different pharmacological properties such as anticonvulsant, analgesic, tranquilizer, antidepressant and anti-anxiety effects. In this study the antidepressant-like effect of aqueous and ethanolic extracts of P. anisum fruit in mice was investigated. Materials and Methods: Forced swimming test (FST) and tail suspension test (TST) were used to determ...
متن کاملAntidepressant- and anxiolytic-like effects of methanolic extract of Salvia spinosa L. in mice
Introduction: Development of new medicines with fewer adverse effects and more efficacies is needed for the treatment of psychiatric disorders. The present study aimed to investigate the putative antidepressant and anxiolytic effects of methanolic extract of Salvia spinosa L. (SS) in mice. Materials and Methods: Elevated plus-maze (EPM) and open field tests (OFT) were conducted to evaluate anti...
متن کاملAntidepressant-like effects of auraptenol in mice
Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Current available antidepressants are not adequate to meet the clinical needs. Here we report that auraptenol, an active component of the traditional Chinese medicine, angelicae dahuricae radix, had antidepressant-like effects in mice models of depression. ...
متن کاملEffects of Hesperidin During Pregnancy on Antidepressant-like behaviour in Postpartum Mice
BACKGROUND:Post-partum depression is the most prevalent form of mental illness and herbal therapies are potential alternatives and adjuncts for its treatment. Hesperidin is the major flavonoid isolated from cit- rus fruits which has neuroprotective, antioxidant and antidepressant activity. OBJECTIVES: We studied the effect of exposure to Hesperidin during pregnancy on postpartum antide- pressan...
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ژورنال
عنوان ژورنال: Brain Research
سال: 2008
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2008.05.088