Antidepressant activity of fingolimod in mice
نویسندگان
چکیده
منابع مشابه
Antidepressant activity of fingolimod in mice
Recent findings indicate that fingolimod, the first oral drug approved for the treatment of multiple sclerosis (MS), acts as a direct inhibitor of histone deacetylases (HDACs) and enhances the production of brain-derived neurotrophic factor (BDNF) in the CNS. Both mechanisms are relevant to the pathophysiology and treatment of major depression. We examined the antidepressant activity of fingoli...
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2015
ISSN: 2052-1707
DOI: 10.1002/prp2.135