Anticoagulation in pregnant women with prosthetic heart valves: A double jeopardy
نویسندگان
چکیده
منابع مشابه
Anticoagulation in pregnant women with prosthetic heart valves: a double jeopardy.
Young women with a prosthetic heat? valve often wish to bear children (1). Pregnancy in such patients is associated with increased risk due to various causes, including increased blood volume and hemodynamic burden, hypercoagulable state of pregnancy leading to increased incidence of thromboemboiic events and the exposure of the fetus to cardiovascular drugs required to treat maternal disease. ...
متن کاملAnticoagulation in pregnant women with prosthetic heart valves.
The combination of heart disease and pregnancy can present a formidable challenge to the clinician entrusted to care for both the mother and fetus. Since most data is retrospective, a definitive prognosis for such a patient may be difficult to obtain. Nevertheless, certain cardiac conditions carry greater risks of maternal mortality than do others. However, even for certain preexisting conditio...
متن کاملAnticoagulation of Pregnant Women With Mechanical Heart Valves
T he management of pregnant women with mechanical heart valves is challenging. Recently, based on small numbers of patients and poor-quality data, correspondence from Aventis Pharmaceuticals Inc has described treatment “failures” and concerns about teratogenicity with the use of the low-molecular-weight heparin (LMWH) enoxaparin. The company issued a “Warning” that enoxaparin should not be used...
متن کاملThe search for a safe and effective anticoagulation regimen in pregnant women with mechanical prosthetic heart valves.
Warfarin, a time-honored treatment for nonpregnant patients with MPHV has been also shown to be effective in the prevention of thromboembolic complications during pregnancy (1–3). Exposure to warfarin in the first 6 to 12 weeks of pregnancy, however, can be associated with a significant risk to the fetus, including spontaneous abortions and warfarin embryopathy (1,3). In addition, the use of or...
متن کاملAnticoagulation for Prosthetic Valves
Implantation of prosthetic valve requires consideration for anticoagulation. The current guideline recommends warfarin on all mechanical valves. Dabigatran is the new generation anticoagulation medication which is taken orally and does not require frequent monitoring. This drug is approved for treatment for atrial fibrillation and venous thromboembolism, but the latest large trial showed that t...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1996
ISSN: 0735-1097
DOI: 10.1016/0735-1097(96)00080-0