Anticoagulant Therapy and Hip Fracture Risk

Warfarin therapy and risk of hip fracture among elderly patients.

STUDY OBJECTIVE To ascertain the relationship between warfarin therapy and subsequent hip fracture in a large elderly population. DESIGN Retrospective, population-based cohort study. SETTING Population-based health care administrative databases for Ontario, Canada. PATIENTS Elderly patients receiving warfarin (52,701 patients), thyroid replacement therapy (40,555), an oral corticosteroid ...

Hormone replacement therapy and risk of hip fracture: population based case-control study. The Swedish Hip Fracture Study Group.

OBJECTIVE To determine the relative risk of hip fracture associated with postmenopausal hormone replacement therapy including the effect of duration and recency of treatment, the addition of progestins, route of administration, and dose. DESIGN Population based case-control study. SETTING Six counties in Sweden. SUBJECTS 1327 women aged 50-81 years with hip fracture and 3262 randomly sele...

Rheumatoid arthritis, corticosteroid therapy and hip fracture.

OBJECTIVE To identify the risk of hip fracture in patients with rheumatoid arthritis and those taking corticosteroids. METHODS In a population based case-control study, we compared 300 consecutive patients with hip fracture aged 50 years and over from a defined district and 600 age and sex matched community controls. RESULTS The risk of hip fracture was increased in patients with rheumatoid...

Cardiovascular diseases and risk of hip fracture.

CONTEXT Recent studies indicate common etiologies for cardiovascular disease (CVD) and osteoporotic fractures. OBJECTIVES To examine the relation between CVD and risk of hip fracture in twins and evaluate the relative importance of genetics and lifestyle factors in this association. DESIGN, SETTING, AND PARTICIPANTS A cohort of all 31,936 Swedish twins born from 1914-1944 was followed up fr...

External hip protectors and risk of hip fracture.