منابع مشابه
Pipecuronium and pancuronium: comparison of pharmacokinetics and duration of action.
The pharmacokinetics of pipecuronium 0.07 mg kg-1 and pancuronium 0.1 mg kg-1 were compared in 39 ASA class I or II patients. Plasma concentrations of these agents were measured for 6 h following administration, using a sensitive and specific capillary gas chromatographic assay. Concentration v. time data were analysed by non-linear regression and fitted to a two- or three-compartment model as ...
متن کاملComparison of action of cholinergic and anticholinesterase agents in glaucoma
The cholinergic agents have the advantages of systemic safety, fewer undesirable local side effects, and usefulness in angle-closure and narrow-angle glaucoma. The powerful cholinesterase inhibitors, on the other hand, produce better diurnal reduction of intraocular pressure, require less frequent administration, and can control many cases whose pressures cannot be otherwise brought to heal. Ne...
متن کاملThe effects of different levels of ventilation on the action of pancuronium in man.
The effect of carbon dioxide on the neuromuscular blocking effect of the non-depolarizing muscle relaxants tubocurarine and gallamine has been known for some time. Kalow (1954) noted that the action of tubocurarine on an isolated muscle preparation was increased by lowering the pH. Payne (1958) found that in the anaesthetized cat the activity of tubocurarine was increased with a reduction of pH...
متن کاملPriming of pancuronium with magnesium.
Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration of pancuronium 100 micrograms kg-1, 95% depression of thumb twitch occurred i...
متن کاملInfluence of suxamethonium on the action of subsequently administered vecuronium or pancuronium.
The effects of suxamethonium were studied on the onset time and duration of action of vecuronium or pancuronium in 45 adult patients anaesthetized with halothane and nitrous oxide. After an intubating dose of suxamethonium, the force of the evoked twitch returned to a value greater than control. The onset of the reduction in force produced by subsequent administration of vecuronium or pancuroni...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1978
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1978.tb08378.x