منابع مشابه
Anticancer mechanisms of cannabinoids.
In addition to the well-known palliative effects of cannabinoids on some cancer-associated symptoms, a large body of evidence shows that these molecules can decrease tumour growth in animal models of cancer. They do so by modulating key cell signalling pathways involved in the control of cancer cell proliferation and survival. In addition, cannabinoids inhibit angiogenesis and decrease metastas...
متن کاملThe use of cannabinoids as anticancer agents
It is well-established that cannabinoids exert palliative effects on some cancer-associated symptoms. In addition evidences obtained during the last fifteen years support that these compounds can reduce tumor growth in animal models of cancer. Cannabinoids have been shown to activate an ER-stress related pathway that leads to the stimulation of autophagy-mediated cancer cell death. In addition,...
متن کاملMechanisms of anticancer drugs
Introduction 34 Principles of chemotherapy 34 Principles of tumour biology 34 Classification of chemotherapeutic agents 37 Limitations of cytotoxic agents 40 Chemotherapy in head and neck cancer 40 Choice of chemotherapy in head and neck cancer 40 Chemotherapy strategies 40 Novel therapies for the future 41 Other novel treatments 44 Conclusion 44 Key points 45 Deficiencies in current knowledge ...
متن کاملEndogenous anticancer mechanisms (EACMs).
Cells capable of starting the track towards cancer are probably abundant in an organism, but the likelihood of any of these cells to evolve to a deadly disease is very low. This occurs in part due to several safekeeping mechanisms shaped by evolution to detect and eliminate potential cancer-forming cells, which will be defined here as endogenous anticancer mechanisms (EACMs). Virtually any cell...
متن کاملEndogenous anticancer mechanisms: metastasis.
Metastases, rather than the primary tumors from which these malignant growths are spawned, are culpable for greater than 90 % of human cancer-associated mortality. Metastases arise through the completion of a series of cell-biological events - collectively termed "the invasion-metastasis cascade" - which involve the dissemination of tumor cells to distant organ sites and their subsequent adapta...
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ژورنال
عنوان ژورنال: Current Oncology
سال: 2016
ISSN: 1718-7729
DOI: 10.3747/co.23.3080