Antibody response to 1.0 and 0.5 mL doses of an inactivated bacterial vaccine against bovine respiratory disease in young Holstein calves: a field trial

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چکیده

Abstract Introduction Early vaccination of cattle with an inactivated commercial bacterial vaccine against bovine respiratory disease has been reported to increase antibody production and can alleviate the disease. However, its dosage little investigated in young Holstein calves. This study addresses need establish guide values for these animals. Material Methods Healthy calves received Histophilus somni , Pasteurella multocida Mannheimia haemolytica intramuscularly at ages 1 4 weeks. Administered doses were 1.0 mL primary booster vaccinations (1.0 + group), 0.5 (0.5 or both group). Results Differences responses between group minor. number a positive response H. was less than half that groups. In logistic regression analysis, although dose positively correlated seropositivity not response. The M. low even after regardless dose. Conclusions be used newborn calves, but may required vaccinations.

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ژورنال

عنوان ژورنال: Journal of Veterinary Research

سال: 2023

ISSN: ['2008-2525']

DOI: https://doi.org/10.2478/jvetres-2023-0037