Antibody manufacture in transgenic animals and comparisons with other systems

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transgenic animals in pharmaceutical and biological research in iran

transgenic (tg) mice are very important models of disease, and have been introduced to biological studies since 1982. they are used for understanding the pathobiology of different diseases, finding targets for pharmacological manipulations, and for the evaluation of efficacy and toxicity of medicines in preclinical studies. many different types of tg mice are available as models for human disea...

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Transgenic animals

The technique of introducing new genetic material into the germline of mammals has been a major development in biotechnology over the last decades. ”Transgenic animals“ are animals whose chromosomes contain stable, integrated copies of exogenous genes, additional copies of endogenous genes or gene constructs. They are frequently created by two different techniques: microinjection of DNA into th...

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Transgenic Animals

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ژورنال

عنوان ژورنال: Current Opinion in Biotechnology

سال: 2002

ISSN: 0958-1669

DOI: 10.1016/s0958-1669(02)00362-2