Antibody-Based Therapies for Emerging Infectious Diseases
نویسندگان
چکیده
منابع مشابه
Antibody-based therapies for emerging infectious diseases.
In the 19th century, it was discovered that immune sera were useful in treating infectious diseases. Serum therapy was largely abandoned in the 1940s because of the toxicity associated with the administration of heterologous sera and the introduction of effective antimicrobial chemotherapy. Recent advances in the technology of monoclonal antibody production provide the means to generate human a...
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The monoclonal antibody (mAb) revolution that currently provides many new options for the treatment of neoplastic and inflammatory diseases has largely bypassed the field of infectious diseases. Only one mAb is licensed for use against an infectious disease, although there are many in various stages of development. This situation is peculiar given that serum therapy was one of the first effecti...
متن کاملEmerging Infectious Diseases
The complex interaction between a microbial pathogen and a host is the underlying basis of infectious disease. By understanding the molecular details of this interaction, we can identify virulence-associated microbial genes and hostdefense strategies and characterize the cues to which they respond and mechanisms by which they are regulated. This information will guide the design of a new genera...
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Disease caused by Shiga toxin-producing Escherichia coli (STEC) ranges from self-limiting diarrhea to hemorrhagic colitis and hemolytic uremic syndrome (HUS). Serotype O157:H7, the most frequently implicated STEC causing hemorrhagic colitis and HUS, has been isolated from large foodborne outbreaks, as well as sporadic cases, in North America and abroad. However, 60 STEC serotypes have been impl...
متن کامل[Emerging infectious diseases].
s of the Fifth International Conference on Tularemia; Woods Hole (MA); 2006 Nov 1–4. [Abstract 210A]. 10. Seabra J, Santos MA, Pereira H, Vicente P, Vasconcelos O, Santo A, et al.Prevalence of Francisella tularensis antibodies in the population of North of Portugal. In: Abstracts of the Prevention and Control of Zoonoses; Cardiff, Wales, UK; 2002 Oct 21–23. Cardiff (Wales); Health Protectio...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 1996
ISSN: 1080-6040
DOI: 10.3201/eid0203.960306