Antibodies to rabbit progesterone receptor: crossreaction with human receptor.

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Monoclonal antibodies to rabbit progesterone receptor: crossreaction with other mammalian progesterone receptors.

A mouse was immunized with purified rabbit uterine cytosolic progesterone receptor (specific activity: 3 nmol of steroid bound per mg of protein). After fusion of its spleen cells with Sp2-OAg myeloma cells, supernatants of 11 hybrid cultures were found to react in both an immunoenzymatic test and a double-immunoprecipitation test with the progesterone receptor. Clones were obtained from the fi...

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Comparison of Estrogen Receptor and Progesterone Receptor in Ductal Carcinoma and Lobular Carcinoma With Regard to Age Prevalence

Background: Breast cancer is one of the most common women’s cancers, and the number of cases is increasing worldwide. Objective: The current study compared invasive lobular carcinoma (ILC) and invasive ductal carcinoma with regard to the prevalence of estrogen receptor (ER), progesterone receptor (PR), and age prevalence. Methods: T...

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Isoform specificity of progesterone receptor antibodies

Progesterone receptors (PR) are prognostic and predictive biomarkers in hormone-dependent cancers. Two main PR isoforms have been described, PRB and PRA, that differ only in that PRB has 164 extra N-terminal amino acids. It has been reported that several antibodies empirically exclusively recognize PRA in formalin-fixed paraffin-embedded (FFPE) tissues. To confirm these findings, we used human ...

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Progesterone receptor in the chick oviduct: an immunohistochemical study with antibodies to distinct receptor components

We performed immunohistochemical studies of chicken oviduct after different fixation procedures, by using antibodies against the progesterone receptor: polyclonal antibodies IgG-G3 against the "8S" form (an oligomere containing progesterone-binding and nonprogesterone-binding units), polyclonal antibodies IgG-RB against the progesterone-binding B subunit, and monoclonal BF4 against the non-prog...

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Progesterone Receptor in the Chick Oviduct: an Immunohistochemical Study with Antibodies to Distinct Receptor Components

We performed immunohistochemical studies of chicken oviduct after different fixation procedures, by using antibodies against the progesterone receptor: polyclonal antibodies IgG-G3 against the "8S" form (an oligomere containing progesterone-binding and nonprogesterone-binding units), polyclonal antibodies IgG-RB against the progesterone-binding B subunit, and monoclonal BF4 against the non-prog...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1981

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.78.3.1426