Antibiotic therapy versus no treatment for chronic endometritis: a case-control study

نویسندگان

چکیده

ObjectiveTo demonstrate the infectious nature of chronic endometritis (CE) in an inductive way by comparing results germ-oriented antibiotic therapy vs. no treatment women with CE.DesignRetrospective, nonconcurrent case-control study.SettingTertiary hysteroscopic center a university teaching hospital.Patient(s)Sixty-four consecutive CE who received (Group A) compared historical group 64 patients refused B).Interventions(s)CE was diagnosed through hysteroscopy, histology, and immunohistochemistry for CD138. Patients both groups were tested twice to evaluate cure rate after or B). For persistent disease, repeated up 3 times. Antibiotics chosen based on endometrial culture (with antibiogram).Main Outcome Measure(s)The primary outcome compare cumulative (defined as percentage without at test cure) between groups.Result(s)Among Group A, 20 (31.25%) experienced resolution 1 cycle, additional 2 cycles, 12 (19.35%) cycles. In cases (18.75%), cycles antibiotics. The A cycle antibiotics significantly higher than that B (32.25% 6%). Similarly, considerably (81.3% Notably, number positive decreased all techniques first second evaluation, whereas third there statistical decrease only hysteroscopy CD138+ cell count but not histology. histology immunohistochemistry.Conclusion(s)Our study demonstrated superiority cure. Accordingly, is inferred. To CE. Retrospective, study. Tertiary hospital. Sixty-four antibiogram). groups. Among immunohistochemistry. Our

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ژورنال

عنوان ژورنال: Fertility and Sterility

سال: 2021

ISSN: ['0015-0282', '1556-5653']

DOI: https://doi.org/10.1016/j.fertnstert.2021.01.018