Antibiotic-Resistant Gene Behavior in Constructed Wetlands Treating Sewage: A Critical Review

The main objective of this review is to evaluate the performance constructed wetlands (CWs) used reduce antibiotic-resistant genes (ARGs) during sewage treatment. To accomplish objective, statistical and correlation analyses were performed using published data determine influence operational design parameters on ARG reduction in CWs. effects parameters, such as different CW configurations, seasonality, monoculture polyculture, support medium, hydraulic retention time (HRT), removals, analyzed. A comparison under configurations showed that hybrid configuration surface flow (SF)–vertical subsurface (VSSF) achieved highest reductions, with values 1.55 ulog. In case, aeration considered an important factor ARGs CWs, it should be future studies. However, reductions not significant (p > 0.05). same behavior was observed when factors analyzed results study show CWs are optimal technologies sewage. combination advanced wastewater can a solution for enhancing reducing spread antibiotic resistance.