Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment
نویسندگان
چکیده
منابع مشابه
The Association Between Genetic Variants in Extended Spectrum Beta-Lactamases and AmpC-producing Gram-Negative Bacilli and Antibiotic Resistance
Background and Objective: A large group of genes associated with extended-spectrum beta-lactamases (ESBL) and AmpC expression is involved in inducing antibiotic resistance in various bacteria. Identifying these genes and assessing their harboring will be crucial in determining the pattern of antibiotic resistance. This study aimed to characterize genetic variants in extended-spectrum beta-lacta...
متن کاملAntibiotic Resistance Pattern and the Prevalence of Extended Spectrum Beta-Lactamases (ESBLs) in Urinary Isolates of Klebsiella Pneumoniae
Abstract Background and Objective: Klebsiella pneumoniae is an opportunistic nosocomial pathogen causing a variety of infections including urinary tract infections, pneumonia, septicemia, wound infections and infections in the intensive care units. Since the ESBL producing Klebsiella pneumoniae strains are increasingly causing urinary tract infections, we aim to assess antibiotic resistance pat...
متن کاملExtended Spectrum Beta-lactamases: Definition, Classification and Epidemiology.
Extended spectrum beta-lactamases (ESBLs) are defined as enzymes produced by certain bacteria that are able to hydrolyze extended spectrum cephalosporin. They are therefore effective against beta-lactam antibiotics such as ceftazidime, ceftriaxone, cefotaxime and oxyimino-monobactam. The objective of the current review is to provide a better understanding of ESBL and the epidemiology of ESBL pr...
متن کاملExtended - spectrum Beta - lactamases
Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...
متن کاملExtended-spectrum beta-lactamases.
At least 30 extended-spectrum beta-lactamases (ESB) have emerged responsible for resistance to indigestible beta-lactams (C3G) since their discovery in West Germany in 1983. Most of them are produced by enterobacteria and essentially K. pneumoniae which appeared susceptible to oxyimino-beta-lactams. A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, bloo...
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ژورنال
عنوان ژورنال: Saudi Journal of Biological Sciences
سال: 2015
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2014.08.002