Antibacterial activity of bone cement containing quaternary ammonium polyethyleneimine nanoparticles
نویسندگان
چکیده
منابع مشابه
Antibacterial activity of bone cement containing quaternary ammonium polyethyleneimine nanoparticles.
Sir, A bone cement mantle is commonly used in orthopaedic surgery, and creates an ideal environment for bacterial growth. Bacterial infection following joint replacement surgery is a catastrophic complication. It is estimated that infections occur in up to about 2% of primary hip and knee replacements, whereas revision surgery carries a 2–3-fold higher risk. The most common bacteria isolated fr...
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A series of gemini quaternary ammonium salts (chlorides and bromides), with various hydrocarbon chain and spacer lengths, were tested. These compounds exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria and were not mutagenic. The strongest antibacterial effect was observed for TMPG-10 Cl (against Pseudomonas aeruginosa ATCC 27853) and TMPG-12 Br (against Stap...
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AIM To evaluate the antibacterial, physicochemical and mechanical properties of two endodontic sealers incorporating quaternary ammonium polyethylenimine (QPEI) nanoparticles at concentrations of 1% and 2% (w/w). METHODOLOGY The sealers tested were AH Plus and Pulp Canal Sealer EWT in the commercial unmodified form or containing 1% or 2% QPEI. Antibacterial activity was evaluated using a dire...
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The antibacterial activity of alanine-derived gemini quaternary ammonium salts (chlorides and bromides) with various spacer and alkyl chain lengths was investigated. The studied compounds exhibited a strong bactericidal effect, especially bromides with 10 and 12 carbon alkyl chains and 3 carbon spacer groups (TMPAL-10 Br and TMPAL-12 Br), with a short contact time. Both salts dislodged biofilms...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2013
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkt441