Antiandrogenic activity of Calotropis procera latex in rats
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چکیده
منابع مشابه
Calotropis procera Latex-Induced Inflammatory Hyperalgesia—Effect of Antiinflammatory Drugs
The milky white latex of plant Calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure. It produces edema on local administration due to the release of histamine and prostaglandins and is associated with hyperalgesia. In the present study we have evaluated the antiedematous and analgesic activity of antiinflammatory drugs against inflammatory response in...
متن کاملHistamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats.
INTRODUCTION Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation induced by latex of C. procera in a rat paw edema model and determined the role of histamine in late...
متن کاملEvaluation of cytotoxic potential of latex of Calotropis procera and podophyllotoxin in Allium cepa root model.
In the present study we have utilized the Allium cepa root tip meristem model to evaluate the cytotoxic and anti-mitotic activities of latex of Calotropis procera (DL) and podophyllotoxin. Standard cytotoxic drug cyclophosphamide and non-cytotoxic drugs cyprohcptadine and aspirin served as controls. Like cyclophosphamide, both DL and podophyllotoxin significantly inhibited the growth of roots a...
متن کاملProtective effect of aqueous suspension of dried latex of Calotropis procera against oxidative stress and renal damage in diabetic rats.
Calotropis species have been used in the traditional medicinal system for the treatment of diseases of the liver and abdomen. In view of the antioxidant and anti-hyperglycemic properties of an aqueous suspension obtained from the dried latex of Calotropis procera, the present study was carried out to evaluate its efficacy in affording protection against alloxan induced changes in rat kidney. A ...
متن کاملCalotropis Procera (Asclepiadaceae) : A Review
Calotropis procera belongs to the family Asclepiadaceae. It is a erect, soft wooded, evergreen perennial shrub. C. procera commonly known as “Akra” and “milk weed”. All the parts (root, stem, leaf and flowers) of C. procera are in common use in traditionally system of medicine. The present paper is an attempt to provide a detailed botanical description, classification, pharmacological study of ...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Reproduction
سال: 2018
ISSN: 2305-0500
DOI: 10.4103/2305-0500.233574