Anti-tumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1
نویسندگان
چکیده
منابع مشابه
Intratumoral IL-15 potentiates radiation-induced anti-tumor immunity
Radiotherapy (RT) can induce T cell-mediated anti-tumor immune responses by multiple mechanisms but is often unable to overcome immunosuppression in the tumor microenvironment. The common gamma-chain cytokines interleukin (IL)-2 and IL-15 promote the proliferation of activated T cells and, therefore, are prime agents for immunotherapy strategies aimed at sustaining anti-tumor T cell responses. ...
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ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2016
ISSN: 0929-1903,1476-5500
DOI: 10.1038/cgt.2016.29