Anti-MuSK Myasthenia Gravis Presenting With Purely Ocular Findings

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Anti-MuSK myasthenia gravis presenting with purely ocular findings.

BACKGROUND Antibodies to a muscle-specific receptor tyrosine kinase (MuSK) have been found in approximately 40% of patients with generalized myasthenia gravis who are seronegative for the antiacetylcholine receptor antibody. Many of the patients with anti-MuSK antibodies have prominent oculobulbar symptoms or weakness of the neck and respiratory muscles, but patients with ocular myasthenia have...

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Myasthenia gravis patients with anti-MuSK antibodies.

In myasthenia gravis (MG) patients without detectable anti-acetylcholine receptor (anti-AChR) antibody, referred to as seronegative myasthenia gravis patients, there is a variable proportion of patients with antibodies against the muscle-specific kinase (MuSK). MuSK antibodies were found in 8 (29.6%) of our 27 patients with generalized MG without anti-AChR antibodies. All these patients were fe...

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Anti-Musk Positive Myasthenia Gravis and Three Semiological Cardinal Signs

Myasthenia gravis (MG) is a relatively uncommon disorder with an annual incidence of approximately 7 to 9 new cases per million. The prevalence is about 70 to 165 per million. The prevalence of the disease has been increasing over the past five decades. This is thought to be due to better recognition of the condition, aging of the population, and the longer life span of affected patients. MG ca...

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A Case of Anti-MuSK Positive Myasthenia Gravis

Anti-MuSK Myasthenia Gravis (MG) is a rare autoimmune neuromuscular junction disorder with poor response to conventional management of MG. We’re reporting a case with typical presentation and clinical course of this disorder. 28-year-old lady presented with prominent oculobulbar, proximal muscle and respiratory muscle progressively worsened for the past 8 months with demonstrable fatigability w...

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Pseudomyopia as a presenting sign in ocular myasthenia gravis.

The presenting symptoms of ocular myasthenia gravis are blepharoptosis and diplopia. These are the result of myasthénie weakening of the levator palpebrae and the extraocular muscles (external ophthalmoplegia), respectively." Blurring of near vision is a frequently as­ sociated symptom, which is due to a fatigue of accommodation (internal ophthalmoplegia)· Blurring of distant vision in ocular m...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2005

ISSN: 0003-9942

DOI: 10.1001/archneur.62.6.1002