ANTI-INFLAMMATORY POTENTIAL OF ALOE VERA IN ORAL MUCOSITIS THERAPY: SYSTEMATIC REVIEW

نویسندگان

چکیده

This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM) therapy. Articles searched using keywords “Oral Mucositis” AND “Aloe vera”, conducted through PubMed, ScienceDirect, and Cochrane Library databases, adapted PICO (Population, Intervention, Comparison, Outcome) framework. The inclusion criteria articles were: Randomized Controlled Trial (RCT) study design; in English; full paper available; published range between 2011-2021 with low risk bias. RoB-tools JADAD Oxford Quality Scoring System was used. writing refers Preferred Reporting Items Systematic Review Meta-analysis (PRISMA) guidelines. A total 5 (five) met a qualitative all showed high quality articles. It found that both solution 70% gel 10% reduction radiotherapy or chemotherapy-induced oral mucositis grade. mouthwash has an equal anti-inflammation effect compare benzydamine on patient radiotherapy-induced mucositis, whereas use other formula containing herbal materials did not show anti-inflammatory effect. Drug formulation can be used as alternative therapy management reduce pain severity mucositis.

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ژورنال

عنوان ژورنال: International Journal of Applied Pharmaceutics

سال: 2022

ISSN: ['0975-7058']

DOI: https://doi.org/10.22159/ijap.2022.v14ti.21