Anti-inflammatory Activity of Ethanolic Leaf Extracts of Thaumatococus Danielli on Iodoacetamide Treated Rats

Anti-inflammatory drugs such as Non-steroidal anti-inflammatory (NSAIDs) are used to reduce swellings and pains caused by inflammation but, long term use of these results in the damage human biological system liver, gastrointestinal tract, etc. Hence, there is need for safer, potent, drugs. activity ethanol leaf extract Thaumatococcus danielli on iodoacetamide treated rats was investigated. Forty-two (42) were divided into seven groups six each. Group 1 (positive control) received 1ml 1% CMC; 2 (negative CMC 0.1% iodoacetamide; 3 50mg/kg (low dose) 4 100mg/kg (high 5 6 7 2.14mg/kg diclofenac. Treatment with T. showed no significant difference (p>0.05) all lymphocyte, RBC, granulocyte, platelet, hemoglobin concentration, hematocrit, mean corpuscular volume count a reduction observed ESR. Moreso, decrease WBC high dose group, increase group administered Ethanolic leaves Thaumaococcus possess an potential, possibly due its embedded phytoconstituents. Keywords: , activity, Hematological studies, Erythrocyte sedimentation rate, Nitric oxide concentration DOI: 10.7176/JNSR/13-10-03 Publication date: May 31 st 2022