Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised ofNigella sativa(Seeds),Hemidesmus indicus(Root), andSmilax glabra(Rhizome) Mediates Its Antihepatocarcinogenic Effects

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Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Root), and Smilax glabra (Rhizome) Mediates Its Antihepatocarcinogenic Effects

The present study investigated the anti-inflammatory effects of a polyherbal decoction comprised of Nigella sativa, Hemidesmus indicus, and Smilax glabra in order to justify its claimed antihepatocarcinogenic activity. Activation of hepatic nuclear factor-kappa B (NF-κB), IκB kinase (IKK α/β) proteins, and TNFα and IL-6 expression was investigated in diethylnitrosamine- (DEN-) induced C3H mice-...

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ژورنال

عنوان ژورنال: Evidence-Based Complementary and Alternative Medicine

سال: 2012

ISSN: 1741-427X,1741-4288

DOI: 10.1155/2012/108626