Anti-Gout arthritic activity of ethanolic and methanolic seed extracts of Pedalium Murex
نویسندگان
چکیده
The present investigation is undertaken to evaluate the comparative anti gout activity of ethanolic (EEPM) and methanolic (MEPM) seed extracts Pedalium murex. Invitro arthritic plant was evaluated using xanthine oxidase protease enzyme inhibition as well membrane stabilization established protocols. In silico studied molecular docking analysis from 10 GCMS derived compounds with that immunuo stimulatory proteins TLR2, TLR4, MMP2 MMP7 find out suitable antagonistic ligand for these proteins. EEPM extract showed better comparable MEPM in terms stabilization. positive control used study. studies among docked MMP7, three namely 11 -Eicosenoic Acid Methyl ester, Docosanoic Acid, ester 1,2Benzendicarboxylic mono (2-ethylhexyl) could inhibit above mentioned immuno there by suppress reactions observed gouty arthritis.
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ژورنال
عنوان ژورنال: International Journal of Health Sciences (IJHS)
سال: 2022
ISSN: ['2550-6978', '2550-696X']
DOI: https://doi.org/10.53730/ijhs.v6ns5.9366