Anti-GAD Antibodies and Periodic Alternating Nystagmus

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منابع مشابه

Anti-GAD antibodies and periodic alternating nystagmus.

BACKGROUND Autoantibodies directed against glutamic acid decarboxylase (GAD-Ab) have recently been described in a few patients with progressive cerebellar ataxia, suggesting an autoimmune physiopathologic mechanism. OBJECTIVE To determine the exact role of GAD-Ab and gamma-aminobutyric acid (GABA)-ergic neurotransmission in the pathogenesis of cerebellar ataxia. DESIGN Case report. SETTIN...

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Acquired Periodic Alternating Nystagmus

대한신경과학회지 22권 5호 548 Periodic alternating nystagmus (PAN) is a rare type of spontaneous horizontal nystagmus, characterized by periodical reverse of direction with a transition period in between. PAN can occur in both congenital and acquired forms. We report a patient with acquired PAN associated with meningoencephalitis. To our knowledge, only a case of congenital PAN has been previously report...

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Periodic alternating nystagmus in humans with albinism.

PURPOSE To quantify the spatial and temporal nature of congenital periodic alternating nystagmus (PAN) and to test the hypothesis that PAN results from a temporal shift in the null zone. METHODS Twenty-five subjects with oculocutaneous albinism (16 tyrosinase negative and 9 tyrosinase positive) and 7 with ocular albinism (5 x-linked and 2 autosomal recessive) participated in the study. Using ...

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Periodic alternating nystagmus. A case report.

A 71-year-old man complained of 5 years of progressive postural instability, more intense when standing up from bed, especially in darkness and during the day when walking on street. It lasted a few seconds and resolved spontaneously. No reference to vegetative symptoms, hearing loss or rotatory movements. Relevant personal clinical antecedents were slowly progressive visual loss that began at ...

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Periodic alternating nystagmus of peripheral vestibular origin.

OBJECTIVES/HYPOTHESIS Periodic alternating nystagmus (PAN) is most commonly found either in its congenital form or after cerebellar/pontomedullary lesions. However, we identified PAN in 10 patients with peripheral vestibular disorders and will try to describe their characteristics to aid in the differential diagnosis between peripheral and central etiologies. STUDY DESIGN Observation of a cas...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2005

ISSN: 0003-9942

DOI: 10.1001/archneur.62.8.1300