Anti-EGFR Therapy in Right-Sided Metastatic Colorectal Cancer: Right or Wrong?
نویسندگان
چکیده
منابع مشابه
Right-sided vs left-sided colorectal cancer.
AV In the analysis of the Cancer and Leukemia Group B (CALGB)/SWOG 80405 trial that we presented at the 2016 annual meeting of the American Society of Clinical Oncology (ASCO), we defined right-sided colon cancer as cancer of the cecum and the ascending colon up to the hepatic flexure. Left-sided colon cancer comprises cancer of the splenic flexure and cancer in regions distal to the splenic fl...
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Treatment with anti-EGFR monoclonal antibodies has been successfully integrated in the continuum of care for metastatic colorectal cancer. The major challenge is the identification of patients who would benefit from treatment. Currently, the best predictor of efficacy is the absence of mutations in KRAS and NRAS genes. Clin Cancer Res; 21(24); 5415-6. ©2015 AACR.See related article by Peeters e...
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There is evidence of a different response to treatment with regard to the primary tumor localization (right-sided or left-sided) in patients with metastatic colorectal cancer (mCRC). We analyzed the different outcomes and biomolecular characteristics in relation to tumor localization in 122 of the 370 patients with metastatic colorectal cancer enrolled onto the phase III prospective multicenter...
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ژورنال
عنوان ژورنال: Journal of the National Comprehensive Cancer Network
سال: 2018
ISSN: 1540-1405,1540-1413
DOI: 10.6004/jnccn.2018.7107