Anti Antidiuretic Hormone Receptor Monoclonal Antibody

Development of a Novel Inhibitory Chimeric Anti-HER2 Monoclonal Antibody

Development of syngeneic monoclonal anti-idiotype antibodies to mouse monoclonal anti-asialoglycoprotein receptor antibody.

Anti-idiotype antibodies (Ab2) play an important role in the homeostasis of immune responses and are related to the development and the disease activity of certain autoimmune diseases. The asialoglycoprotein receptor (ASGPR) is considered one of the target antigens in the pathogenesis of autoimmune chronic active hepatitis (AIH). We previously developed a mouse monoclonal antibody (clone 8D7) w...

CONFIRM anti-Progesterone Receptor (PR) (1E2) Rabbit Monoclonal Primary Antibody

CONFIRM anti-Progesterone Receptor (PR) (1E2) Rabbit Monoclonal (IgG) is intended for laboratory use for the qualitative detection of progesterone receptor (PR) antigen in sections of formalin-fixed, paraffin-embedded tissue on a VENTANA automated slide stainer with VENTANA detection kits and ancillary reagents. CONFIRM antiPR (1E2) is directed against an epitope present on human progesterone r...

Mouse Anti-Tetracycline Monoclonal Antibody

Product Overview: Mouse monoclonal antibody to tetracycline. Immunogen: Tetracycline-KLH Conjugate Clone: K88Y88 Host animal: Mouse Source: Mouse Ascites Purity: Protein A Affinity Chromatography. Buffer: 0.01 moL/L pH 7.4 Phosphate Buffer Solution. Protein Content: 1 mg/mL Appearance: Clear Colorless Solution Introduction: Tetracycline is a broad-spectrum polyketide antibiotic produced by the ...

Chlorpropamide upregulates antidiuretic hormone receptors and unmasks constitutive receptor signaling.

The mechanism by which chlorpropamide (CP) treatment promotes antidiuresis is unknown. CP competitively inhibited antidiuretic hormone (ADH) binding and adenylyl cyclase (AC) stimulation (inhibition constants K(i) and K'(i) of 2.8 mM and 250 microM, respectively) in the LLC-PK(1) cell line. CP (333 microM) increased the apparent K(a) of ADH for AC activation (0.31 vs. 0.08 nM) without affecting...