Annotation extension through protein family annotation coherence metrics
نویسندگان
چکیده
منابع مشابه
Annotation extension through protein family annotation coherence metrics
Protein functional annotation consists in associating proteins with textual descriptors elucidating their biological roles. The bulk of annotation is done via automated procedures that ultimately rely on annotation transfer. Despite a large number of existing protein annotation procedures the ever growing protein space is never completely annotated. One of the facets of annotation incompletenes...
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In the wake of the many fruitful genome projects, tools to aid the annotation of proteomic data are sorely needed. Building from relatively simplistic approaches to an integrated system developed in collaboration with text mining experts, we have created tools capable of producing core annotation for protein families; but many challenges remain. Extending and improving these tools should have w...
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For bioscientists studying protein structure and function, the Protein Family Alignment Annotation Tool (Pfaat) is a useful and simple program for annotating collections of proteins. This open-source software includes methods for viewing and aligning protein families, and for annotating sequence structure and residues with known functions. It offers new options to aid the study of proteins, and...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2013
ISSN: 1664-8021
DOI: 10.3389/fgene.2013.00201