Animal Models of Hepatitis B Virus Infection–Success, Challenges, and Future Directions
نویسندگان
چکیده
منابع مشابه
Alcoholic hepatitis: current challenges and future directions.
Alcoholic hepatitis is a distinct clinical syndrome among people with chronic and active alcohol abuse, with a potential for 30%-40% mortality at 1 month among those with severe disease. Corticosteroids or pentoxifylline are the current pharmacologic treatment options, but they provide only about 50% survival benefit. These agents are recommended for patients with modified discriminant function...
متن کاملPathogenesis of Epilepsy: Challenges in Animal Models
Epilepsy is one of the most common chronic disorders affecting individuals of all ages. A greater understanding of pathogenesis in epilepsy will likely provide the basis fundamental for development of new antiepileptic therapies that aim to prevent the epileptogenesis process or modify the progression of epilepsy in addition to treatment of epilepsy symptomatically. Therefore, severa...
متن کاملChronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions
Recent guidelines of the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver 2008 update of the "Asian-Pacific consensus statement on the management of chronic hepatitis B" offer comprehensive recommendations for the general management of chronic hepatitis B (CHB). These recommend...
متن کاملAnimal Models of Respiratory Syncytial Virus Pathogenesis and Vaccine Development: Opportunities and Future Directions
Human respiratory syncytial virus (HRSV) is the leading cause of respiratory failure and viral death in infants (Thompson et al., 2003). In HRSV bronchiolitis, plugs of mucus, epithelial cell debris, and innate inflammatory cells obstruct the airways leading to pulmonary obstruction (Aherne et al., 1970; Lugo and Nahata, 1993). In autopsy lung tissues from fatal HRSV disease cases, epithelial d...
متن کاملResearch into Future Control of Hepatitis B Virus and Study of Anti-HBC as the Most Sensitive Test for B Virus Carriers in Iran
Two antigen-antibody systems were Out of 42 sera from patients with acute viral hepatitis 33 were positive for HBsAg,all HBsAg positive individuals possessed anti-HBc. From 11 blood donors sera 8 were positive for HBsAg and 9 were Positive for anti-HBc;2 leprosy sera were tested,both of them were positive for HBsAg and anti-HBc. 5 miscellaneous samples,z·were positive for HBsAg and anti-HBc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Viruses
سال: 2021
ISSN: 1999-4915
DOI: 10.3390/v13050777