Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF- B pathway
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چکیده
منابع مشابه
Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF-kappaB pathway.
OBJECTIVE To evaluate the effects of angiotensin II (Ang II) treatment on apoptosis of fibroblast-like synoviocytes (FLS) from patients with osteoarthritis (OA) and rheumatoid arthritis (RA). METHODS AT1 receptor expression was detected by western blotting and flow cytometry. Apoptosis induction was quantified by nucleosome ELISA and by TUNEL; cell proliferation was determined by a bromodeoxy...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2007
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kem092