Angioscopic Assessment of Arterial Repair Following Biodegradable Polymer-Coated Biolimus A9-Eluting Stent Implantation - Comparison With Durable Polymer-Coated Sirolimus-Eluting Stent -

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Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial.

BACKGROUND Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting. METHODS This randomised, ...

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The twelve-month outcome of biolimus eluting stent with biodegradable polymer compared with an everolimus eluting stent with durable polymer.

INTRODUCTION Drug-eluting stents (DES) have significantly decreased the need for repeat coronary revascularization but concerns remain regarding the safety of first and second generation DES. We compared the safety and efficacy of a biolimus-eluting stent (with biodegradable polymer) with an everolimus-eluting stent (with durable polymer) one. METHODS We performed a randomized trial to compar...

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A randomized comparison of novel biodegradable polymer- and durable polymer-coated cobalt-chromium sirolimus-eluting stents.

OBJECTIVES The aim of this study was to investigate the hypothesis that a novel biodegradable polymer-coated, cobalt-chromium (CoCr), sirolimus-eluting stent (BP-SES) is noninferior in safety and efficacy outcomes compared with a durable polymer (DP)-SES. BACKGROUND No randomized trials have the compared safety and efficacy of BP-SES versus DP-SES on similar CoCr platforms, thereby isolating ...

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In percutaneous coronary interventions, drug-eluting stents (DESs) have reduced the risk of restenosis and repeat revascularization compared with bare-metal stents. The secondgeneration DESs with thinner stent struts have improved safety and efficacy compared with the first-generation DESs and has been associated with a reduced risk of late stent thrombosis. The persistence of polymer material ...

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The postulated relationship between nonbiodegradable polymers and LST has led to a concerted effort to seek alternative biodegradable polymers for drug delivery. Bioabsorbable coatings with a degradation period matched to that of the drug elution may be a better alternative, clinically and economically. The purpose of this study was to evaluate the safety and the efficacy of the novel sirolimus...

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ژورنال

عنوان ژورنال: Circulation Journal

سال: 2011

ISSN: 1346-9843,1347-4820

DOI: 10.1253/circj.cj-10-0776