Angiogenic Factors Play a Significant Role in Nasal Airway Remodeling in Allergic Rhinitis

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Angiogenic Factors Play a Significant Role in Nasal Airway Remodeling in Allergic Rhinitis

© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org The definition of remodeling is “model again or differently, reconstruct.” In the airway, reaction to chronic inflammatory conditions can lead to changes in the structural components of the airway wall, known as airway remodeling. Airway r...

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Role of Angiogenic Factors in Airway Remodeling in an Allergic Rhinitis Murine Model

PURPOSE There is growing evidence that nasal airway remodeling occurs in allergic rhinitis (AR). Although angiogenesis is an important component of airway remodeling in asthma, its involvement in AR has been little studied. Furthermore, information regarding the role of potent angiogenic factors, such as vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF), in the...

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Local Allergic Rhinitis in Pediatric Patients: is IgE Dosage in Nasal Lavage Fluid a Usefull Diagnostic Method in Children?

Local Allergic Rhinitis (LAR) is an emerging disease. However, its incidence in the pediatric population has not yet been studied. The gold-standard for the diagnosis is the nasal provocation test that is not everywhere available and difficult to apply in children. The aim of our study is to evaluate the nasal lavage fluid IgE as a biomarker of LAR in children. 54 pediatric patients [IQR 4.0-12...

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A significant increase in expression of FOXP3 and IL-17 genes in patients with allergic rhinitis underwent accelerated rush immunotherapy

Objective(s): Allergic rhinitis (AR) is a common hypersensitivity disease worldwide. Immunotherapy has been performed as the best treatment for years. This study aimed to study the gene expression pattern of immune system cells following an accelerated rush immunotherapy protocol (ARIT) in patients with AR.Materials and Methods: Fifteen ...

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Effect of Botulinum Neurotoxin A Injection into the Submucoperichondrium of the Nasal Septum in Reducing Idiopathic Non-Allergic Rhinitis and Persistent Allergic Rhinitis

Introduction: Submucoperichondrial injection of botulinum neurotoxin A (BTA) in the nasal septum is a promising therapeutic option in the treatment of persistent allergic rhinitis (AR) and non-allergic rhinitis, and is safer and more effective than intraturbinate injection in reducing clinical symptoms.   Materials and Methods: Forty patients diagnosed with persistent AR or non-allergic rhiniti...

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ژورنال

عنوان ژورنال: Allergy, Asthma and Immunology Research

سال: 2012

ISSN: 2092-7355,2092-7363

DOI: 10.4168/aair.2012.4.1.2