Anesthesia in Patients with Positive Direct Coombs Test. Report of Three Cases

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Anesthesia in patients with positive direct coombs test: report of three cases.

BACKGROUND AND OBJECTIVES Neoplasias can be associated with autoimmune hemolytic anemia (AHA) with the consequent blood incompatibility that hinders blood transfusion. The authors describe and discuss the conduct in three patients undergoing surgical intervention for neoplastic disease with positive Coombs Test (CT), and the impossibility to determine the blood type. CASE REPORT 1st case: 87-...

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Anemia with positive direct Coombs' test induced by trypan blue.

as evidence of autoimmune phenomena. The experimental production of positive antiglobulin tests by drugs and chemical agents, however, has suggested that nonimmunologic mechanisms may also be responsible for protein coating of erythrocytes.2’3 During attempts to produce tumors of the reticuloendothelial system in rats by injection of trypan blue, an anemia, chacacterized by increased ervthrocyt...

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Changing incidence of positive direct Coombs test in inbred NZB-BL mice.

The. inbred NZB/BL mouse has been shown by Bielschowsky, Helyer, and Howie (1959) to develop auto-immune haemolytic anaemia spontaneously, and this disorder has been considered to be genetically determined (Holmes and Burnet, 1966). Burnet and Holmes (1962) described a characteristic thymic change in this 'auto-immune' strain of mice; and certain renal lesions have been noted (Holmes and Burnet...

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ژورنال

عنوان ژورنال: Brazilian Journal of Anesthesiology

سال: 2010

ISSN: 0034-7094

DOI: 10.1016/s0034-7094(10)70009-x