Anemia de Fanconi: Consideraciones actuales
نویسندگان
چکیده
منابع مشابه
Fanconi anemia
What is it? Fanconi anemia (FA) is an autosomal recessive human disease characterized by congenital malformations, bone marrow failure and cancer. FA patients often develop leukemia and/or squamous cell carcinomas of the head and neck or gynecologic system. FA cells are hypersensitive to DNA crosslinking agents, such as mitomycin C (MMC) or diepoxybutane (DEB), and the syndrome is believed to r...
متن کاملFrequency of Hypothyroidism in Fanconi Anemia
Background: Fanconi anemia (FA) is a rare, autosomal recessive (AR) and multifactorial disorder. A high prevalence of FA observed in Iran is perhaps due to the high rate of consanguineous marriages. This study investigates the extent of short stature in patients with FA, the frequency of hypothyroidism in FA and the correlation between height and hypothyroidism. Methods: Eighteen patients with ...
متن کاملMutated Fanconi anemia pathway in non-Fanconi anemia cancers
An extremely high cancer incidence and the hypersensitivity to DNA crosslinking agents associated with Fanconi Anemia (FA) have marked it to be a unique genetic model system to study human cancer etiology and treatment, which has emerged an intense area of investigation in cancer research. However, there is limited information about the relationship between the mutated FA pathway and the cancer...
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Much has been studied about the effects of Geert Hofstede’s National Culture dimensions. However, regarding Information Systems Research, most works have focused on information technology adoption and use, and impacts on task performance. This research in progress attempts to explore factors that need to be considered for web interfaces design. Multinational firms tend to standardize applicatio...
متن کاملFanconi ’ s anemia
Key-words Name of the disease Definition Differential diagnosis Frequency Clinical description Treatment Etiology Genetic counselling Prenatal diagnosis Unresolved questions References
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ژورنال
عنوان ژورنال: Anales del Sistema Sanitario de Navarra
سال: 2003
ISSN: 1137-6627
DOI: 10.4321/s1137-66272003000100006