Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids
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چکیده
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Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids.
Androgen receptor function is required for male embryonic sexual differentiation, pubertal development and the regulation of spermatogenesis in mammals. During spermatogenesis, this requirement is thought to be mediated by Sertoli cells and its genetic and pharmacological disruption is manifested in spermatocytes as meiotic arrest. Through studies of a hypomorphic and conditional allele of the ...
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ژورنال
عنوان ژورنال: Development
سال: 2004
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00957