Ancient thioredoxins evolved to modern-day stability–function requirement by altering native state ensemble

International Clinical Trials Day 2014—ancient and modern needs

Today is International Clinical Trials' Day, which is always celebrated around the 20th of May, the day during the Spring of 1747 when James Lind began a clinical trial that produced useful information to understand, treat and prevent scurvy. The reason why many of us still dedicate a celebration to James Lind goes well beyond the intrinsic value of his trial, which actually had many flaws and ...

Toxikon: an ancient word fits modern-day poisons.

On Greek, Ancient and Modern (but Rather Ancient than Modern)

In this paper a few applications of the current implementation of R are given. These applications concern typesetting problems that cannot be solved by TEX (consequently, by no other typesetting system known to the authors). They cover a wide range, going from calligraphic script fonts (Adobe Poetica), to plain Dutch/Portuguese/Turkish typesetting, to vowelized Arabic, fully diacriticized schol...

A History of Dystonia: Ancient to Modern

Before 1911, when Hermann Oppenheim introduced the term dystonia, this movement disorder lacked a unifying descriptor. While words like epilepsy, apoplexy, and palsy have had their meanings since antiquity, references to dystonia are much harder to identify in historical documents. Torticollis is an exception, although there is difficulty distinguishing dystonic torticollis from congenital musc...

Ancient and modern rangefinders

OAKOC is an Army acronym used for planning operations: it stands for Observation and fields of fire, Avenues of approach, Key and decisive terrain, Obstacles, and Cover and concealment. The first point is therefore the Observation and fields of fire. It means that it is necessary to answer the following questions [1]: What can you see throughout your area? What fields of fire will you have in t...